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In this taut and fascinating novel, the bestselling, New York Times bestselling and National Book Award-winning author of The Sacrifice, The Accursed, and Lovely, Dark, Deep examines the mysteries of memory, personality, and identity and pierces the enigmatic force that drives human liveslove.

In 1965, neuroscientist Margot Sharpe meets the attractive, charismatic Elihu Hoopesthe man without a shadowwhose devastated memory, unable to store new experiences or to retrieve the old, will make him the most famous and most studied amnesiac in history. Over the course of the next thirty years, Margot herself becomes famous for her experiments with E. H.and inadvertently falls in love with him, despite the ethical ambiguity of their affair, and though he remains forever elusive and mysterious to her, haunted by mysteries of the past.

The Man Without a Shadow tracks the intimate, illicit relationship between Margot and Eli, as scientist and subject embark upon an exploration of the labyrinthine mysteries of the human brain. Where does memory reside? Where is love? Is it possible to love an individual who cannot love you, who cannot remember you from one meeting to the next?

Made vivid by her exceptional eye for detail and her keen insight into the human psyche, The Man Without A Shadow is a unique story of forbidden love, a kind of secret, evolving marriage, depicted in Joyce Carol Oatess tight, impassioned prose. It is an uncanny, ambitious, and structurally complex novel that penetrates the mind and illuminates the heart.