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This breakout novel from Giller Prize finalist Michael Helm is a genre-bending work of astonishing vision and a dazzling story of our times.

A neuroscientist retreats to a secluded cabin in the woods, intending to blow the whistle on a pharmaceutical company and its creativity drug gone wrong. A failed poet is lured to Rome as a “literary detective” to decode the work of a mysterious Internet poet who seems to write about murders with precise knowledge of private details. On the heels of a life crisis, a virologist discovers her identity has been stolen by a conceptual artist in whose work someone always goes missing.After Jamesis an audacious, masterful novel, told in three connected parts, each gesturing toward a type of genre fiction–the gothic horror, the detective novel, and the apocalyptic. As the novel unfolds in great cities, remote regions, and deadly borderlands, it weaves connections both explicit and subtle, pulli