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John P. Schaefer was only thirty-six-years old when he assumed the role of fifteenth President of the University of Arizona in 1971. The son of hardworking German immigrants, Schaefer grew up in Queens, New York where childhood centered on sports, academics, and the great outdoors. Earning a PhD in Chemistry in 1958, Dr. Schaefer’s career skyrocketed through the ranks of academia moving from junior faculty to university president in a mere decade. As President, he led the University of Arizona through a transformational period of growth and is credited with securing the university’s status as a top-tier research institution. A Chance to Make a Difference recounts poignant, eye-opening, and often humorous stories from childhood to presidency, revealing the characteristics of an inspiring university leader.