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This Element argues that Plato’s medical language in political contexts is not mere metaphor but a medical model of political analysis. Centering on the Republic, it shows how Plato adopts, critiques, and reworks Hippocratic ideas to diagnose, explain, evaluate, and treat political conditions. The payoff is a solution to a central puzzle: how the ideal city can be exceptionally stable yet liable to degenerate into vice. Its stability, I argue, consists in a robustness and resilience analogous to bodily health, sustained by protective institutions and practices; its fragility lies in the inevitable fallibility of those protections, which cannot indefinitely prevent, arrest, or reverse corruption over time. The Element then identifies a corrupt paideia-understood as a city-wide system of acculturation-as the singular, foundational cause of political degeneration, and closes by drawing lessons about the limits and prospects of genuine reform.